Tactical Pharma 800k DPS | Rank 1 Global Player Build

What This Build Does

Build credit: RogueMadras. He just released an updated build video walking through his latest Tactical Pharma setup, the same build that pushed him to Rank 1 Global. You can also watch his original gameplay breakdown.

We originally covered this build as the “Geneva Suggestion.” RogueMadras has since optimized it further for Division Resurgence Season 2, so we’re updating everything. 800k+ DPS. Rank 1 Global. On the Tactical Pharma specialization.

This is a skill-damage build that uses Chemical Trap and Oxidizing Hive as slotted skills, with Oxidizing Swarm as the signature ability providing automated corrosive pressure. Weapons exist to generate Engineering stacks, not to kill. The core loop is straightforward: throw Chemical Trap at a choke point, swap weapons to trigger Backup Battery (+22.50% Engineering) and Prime Engineer 2 (+31.50% Engineering), then deploy Oxidizing Hive for sustained corrosive damage. Pop Oxidizing Swarm (signature) when available for burst pressure. Swap to MK16 to stack Skill Multi-Shot, and repeat as cooldowns come back. The build scales entirely through Engineering, Skill Crit, and Skill Multi-Shot.

RogueMadras’s Stats (26.61k Power Score)

His actual in-game numbers for reference:

Tactical Pharma Gear and Loadout

Gear

Where we differ from RogueMadras’s current setup:

• Chest: He’s running Energize 2 (+25% Skill Damage for 8s on Medical Kit use; Multi-Shot refreshes duration) but recommends Glass Cannon as best-in-slot. T2 gives +28% Damage, T1 gives +20%.
• Backpack: He has Skill Cooldown Recovery in one slot but doesn’t recommend CDR. We use Skill Crit Chance instead. Alternative talent: Minion Training (+36% Skill Crit Hit Damage for 12s on skill crit kills).
• Gloves: He has Skill Duration but says to swap it. We use Skill Intensity because higher damage per tick matters more than longer duration.

Loadout

Skill Mods

Use Intensity, not Radius. Radius increases area coverage. Intensity increases damage per tick. Intensity on all skills, always.

Why Each Gear Piece Matters

Jackpot 4-Piece

• 2pc: Skill Radius +12.00%. Wider coverage, more enemies hit per deployment.
• 3pc: Skill Critical Chance +10.80%. Consistent crits on every tick.
• 4pc: Skill Critical Damage +24.00%. This is where the damage ceiling lives.

Fire Cycle 2-Piece

• 2pc: Skill Crit Damage +12.00%. Combined with Jackpot 4pc, that’s +36% Skill Crit Damage from set bonuses alone, before any gear rolls or talents.

Chest: Glass Cannon (T2)

+28% Damage (T2) / +20% Damage (T1). Increases incoming damage as a tradeoff.

Best-in-slot for maximum DPS. Glass Cannon increases all damage you deal, including skill damage, based on current community testing. Position 30 meters behind the fight to offset the squishiness.

Alternative: Energize 2 (+25% Skill Damage for 8s on Medical Kit use, refreshed by Multi-Shot procs). Safer, less raw output. RogueMadras is currently running this but recommends Glass Cannon.

Backpack: Prime Engineer 2

Deploying a Skill at full Health grants +31.50% Engineering for 12 seconds.

One of the largest single Engineering boosts in the game. Triggers on every Chemical Trap deployment at full HP. Stacks with Backup Battery’s +22.50% on weapon swap for a combined +54% Engineering.

Alternative: Minion Training. Skill Crit Kill Hits grant +36% Skill Crit Hit Damage for 12 seconds.

Skill Multi-Shot: Why 40% Is Enough

Through Tactical Augmentation you get 2 talents that boost Skill Multi-Shot damage, so the procs you land hit significantly harder. ~40% Skill Multi-Shot Chance is the target. Going higher trades Crit Chance or Intensity for diminishing returns.

Best OS Protocol for Tactical Pharma

RogueMadras recommends Rampart as the best OS Protocol. He is currently running Brains Over Brawn. Here are all viable options:

1. Rampart (High-End / Gold) — RECOMMENDED BEST

“While immobile, grants +5% Damage for 1 second, up to 6 stacks. This bonus resets upon moving.”

“Immobile” means not moving your character. Just standing still. On a skill build where you position behind cover and deploy, this is a free +30% Damage with minimal effort. Rampart is recommended over alternatives because Glass Cannon and Prime Engineer already push your Engineering high enough that Rampart’s flat +30% Damage acts as a multiplicative layer on top — rather than stacking more Engineering from the same additive pool.

Stats: Skill Critical Chance +18.00%, Engineering +97, Skill Damage +77, Health +2,554.

2. Brains Over Brawn (Specialized / Blue) — What He’s Currently Running

“Hits deal additional damage equal to 48% Engineering.” (at Level 50)

Every skill tick deals bonus damage equal to nearly half your Engineering stat. With skills hitting multiple enemies across dozens of ticks per second, this adds up fast.

Stats (at Lv50): Engineering +268, Skill Damage +215, Health +7,052.

+268 Engineering on a Blue OS is more than most High-End protocols give. Strong talent, strong stats, just not Rampart.

3. Chain Reaction (Superior / Purple) — Strong Alternative

“Kills grant +7.50% Skill Intensity for 10 seconds, up to 2 stacks.” (+15% total)

Stays permanently active on a build that clears rooms every 10 seconds. Feeds directly into Chemical Trap damage.

Stats (at Lv50): Skill Critical Chance +28.80%, Engineering +358, Skill Damage +286, Health +9,402.

RogueMadras recommends at least Talent Rank 3. Below that, the bonus doesn’t justify the slot.

4. Tactical Layering (High-End / Gold) — Solid Option

“Deploying a Skill grants +15% Engineering, up to 3 stacks.” (+45% max)

Every Chemical Trap and Oxidizing Hive deployment stacks Engineering. Stays active permanently on a skill-spam build.

Stats: Skill Intensity +15.00%, Engineering +97, Skill Damage +77, Health +2,554.

5. Ambusher (Superior / Purple) — Untested

“Being immobile for 3 seconds grants +22.50% Engineering.”

Similar concept to Rampart with a 3-second wind-up instead of per-second stacking. Neither RogueMadras nor we have tested this yet. The ramp-up punishes repositioning, but on a stationary skill build it could be strong.

Stats: Skill Intensity +12.00%, Engineering +77, Skill Damage +62, Health +2,043.

Weapon Talents and Attachments

Both weapons exist to generate buffs. The Vector stacks Engineering through Backup Battery, the MK16 stacks Skill Multi-Shot through Multi-Pronged Attack.

Primary: Vector 45 ACP (T2, SMG)

T2 Vector rolled for Engineering. High RPM empties magazines fast, which means faster buff procs.

• Backup Battery: Swapping to this weapon grants +22.50% Engineering for 8 seconds (8s cooldown). Core Engineering injection. Swap on cooldown, every 8 seconds.
• Backup Magazine: Swapping to this weapon reloads your second weapon after 4 seconds. The MK16 reloads itself while you fire the Vector. Keeps the rotation smooth.

Attributes: Skill Intensity + Skill Critical Damage.

RogueMadras is running Swift Taunt 2 as his second talent but doesn’t recommend it. Use Backup Magazine instead. In Sync is a viable alternative to Backup Battery (+9% Skill Damage on weapon hits, +9% Weapon Damage on skill hits, doubled when both active).

Secondary: MK16 (AR)

The Multi-Shot engine. Swap to this to stack Multi-Shot chance and boost Skill Crit Damage.

• Multi-Pronged Attack: Hits grant +3.60% Skill Multi-Shot Chance for 10 seconds, up to 5 stacks (+18% total). Missed hits remove 1 stack.
• Multitasking: Dealing damage to 3 enemies within 5 seconds grants +30% Skill Critical Damage for 12 seconds (8s cooldown). Easy to proc when fighting rooms of enemies.

Attributes: Skill Intensity + Skill Critical Damage.

RogueMadras is running Bloodlust 2 + Adaptation on his MK16, which is not ideal for this build. Use the recommended talents above.

Attachments & Tactical Augmentation

All weapon attachments should be Engineering.

Tactical Augmentation: If your weapon offers an augment that boosts Skill Multi-Shot Damage, prefer that option. Augmentation options vary by weapon type and rarity — not every weapon offers the same perks. Look for anything that increases Skill Multi-Shot Damage or Skill Intensity. The exact rolls depend on what’s available for your specific weapon.

Loot Quick-Reference for Tactical Pharma